Thursday night lights: Can the 49ers topple the Rams, or is LA set to dominate in this high-stakes October 2 showdown?tl

49ers Preview

The week five NFL schedule will kick off on Thursday night with a matchup between the San Francisco 49ers and the Los Angeles Rams from SoFi Stadium. Get ready for all the football action with our NFL Picks. The 49ers (3-1) rank second in the league in passing offense (280 ypg) and are averaging 20 points per game. On Sunday, San Francisco trailed by 11 points at halftime and committed four turnovers during a 26-21 home loss versus Jacksonville.

San Francisco QB Brock Purdy completed 22 of 38 passes for 309 yards and two touchdowns. All-Pro RB Christian McCaffrey contributed 141 yards from scrimmage and caught an eight-yard touchdown pass. LB Dee Winters recorded 10 tackles (9 solo) in a losing effort for the 49ers.

Rams Preview

49ers to Celebrate Inspire Change on 'Thursday Night Football' vs. LA Rams

The Los Angeles Rams have reached the playoffs in four of the previous five seasons and are locked in a three-way tie for first place in the NFC West Division. The Rams (3-1) rank fourth in the league in total offense (388.3 ypg) and are scoring 25 points per contest. Last week, Los Angeles racked up 462 yards of offense during a 27-20 home victory versus Indianapolis.

Los Angeles broke a 20-20 tie with 93 seconds remaining on an 88-yard touchdown pass from Matthew Stafford to Tutu Atwell. Stafford evened the score two minutes earlier on a 9-yard strike to Puka Nacua, who finished with a game-high 170 receiving yards. Kyren Williams added 77 rushing yards for the Rams.

49ers vs Rams Pick

6 stats to know for Rams vs. 49ers on Thursday night

San Francisco QB Brock Purdy is bothered by turf toe and his status for this game is uncertain. TE George Kittle (hamstring) is currently on injured reserve and will not play. The Rams are healthier and are the better team, which is even more important on a short week. Take Los Angeles to win and cover at home. Final Score Prediction, Los Angeles Rams win 30-17.

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