Mac Jones’ Perfect Run Ends as 49ers Fall to Buccaneers — and Questions Mount Across Former Patriots QBs

Mac Jones is undefeated no more.

The San Francisco 49ers quarterback suffered his first loss as the team’s starter on Sunday, falling 30–19 to the Tampa Bay Buccaneers in a game that exposed both promise and growing pains for the young signal-caller. Entering Week 6, Jones had led the 49ers to three straight wins since stepping in for the injured Brock Purdy, looking sharp and composed in each outing. But against Tampa Bay, the story shifted.

Jones completed 27 of his 39 passes for an impressive 347 yards — proof that his arm talent and pocket presence continue to shine — yet the two costly interceptions ultimately swung momentum in the Buccaneers’ favor. Those mistakes, paired with a sluggish ground attack and inconsistent protection up front, doomed San Francisco’s hopes of staying unbeaten under their new quarterback.

From Perfection to Pressure

For Jones, this was the first true setback of what had been a rejuvenating chapter. After his roller-coaster tenure in New England, many wondered if the former 2021 first-round pick could thrive under a new system. The 49ers seemed to unlock a version of him that was both more confident and better supported. His early wins sparked national conversation — could Kyle Shanahan’s scheme finally maximize the talent once touted as the Patriots’ next franchise cornerstone?

But Sunday’s loss served as a reminder that success in San Francisco doesn’t come without scrutiny. With Purdy still sidelined and nursing injuries of his own, the 49ers now face tough decisions ahead of Week 7. Who starts against the Atlanta Falcons in Sunday Night Football — the seasoned, battle-tested Jones, or a potentially recovered Purdy returning to reclaim his spot?

As Shanahan told reporters postgame, “We’ve got two guys capable of leading this team. The decision will come down to health, rhythm, and what gives us the best shot to win.”

That uncertainty looms large. Jones’ 347-yard performance showed flashes of brilliance — quick reads, accurate throws on the move, and resilience under pressure. But the turnovers were glaring reminders that timing and chemistry still need work. The loss dropped the 49ers to 4–2, and while they remain in strong playoff position, their next steps at quarterback could define the tone of their season.

Patriots Roots Still Run Deep

Interestingly, Jones wasn’t the only former New England quarterback in the spotlight on Sunday. Across the league, familiar faces from the Patriots’ past were navigating their own pivotal moments.

In Arizona, Jacoby Brissett got the nod as the Cardinals’ starter, filling in for Kyler Murray, who remains sidelined with a mid-foot sprain. Brissett, another former Patriot who spent the 2024 season back in New England during his second stint, put together a respectable performance despite the loss — completing 27 of 44 passes for 281 yards, two touchdowns, and one interception in a 31–27 defeat to the Indianapolis Colts.

The Cardinals showed heart in the narrow loss, and Brissett’s leadership drew praise from teammates. “Jacoby’s calm in the huddle, he keeps everyone believing,” said wide receiver Michael Wilson. “We just fell short at the end.”

Murray’s return to practice on Friday was a positive sign, but with his recovery still ongoing, Brissett may need to carry the load for at least another week. Head coach Jonathan Gannon hinted that the medical staff would be cautious with their franchise quarterback, saying, “We won’t rush it. When Kyler’s ready, he’ll play — until then, Jacoby gives us a chance.”

A Weekend of Reflection for Former Patriots

Meanwhile, another former New England quarterback made headlines for a far different reason — one that had nothing to do with on-field struggles. Cam Newton, who last played in the NFL in 2021 and officially announced his retirement earlier this year, returned to Auburn University on Saturday for an emotional ceremony as his alma mater retired his iconic No. 2 jersey.

The former Heisman Trophy winner received a roaring ovation at Jordan-Hare Stadium, standing proudly as highlights from his electrifying 2010 season played on the big screen. “Auburn gave me everything,” Newton said through tears. “This number isn’t just mine — it’s for everyone who believed in me when nobody else did.”

For Patriots fans watching from afar, it was a poignant weekend — three quarterbacks once tied to New England’s post-Brady era, each at different crossroads. Jones is trying to prove he can lead a contender. Brissett is fighting to extend his starting opportunity. Newton is embracing his legacy after closing a remarkable career.

What’s Next in San Francisco

Back in the Bay Area, the focus remains firmly on the 49ers’ quarterback situation. Purdy’s health and Jones’ response to adversity will dominate headlines heading into Week 7. If Jones starts again, it will be a crucial test of his mental toughness and adaptability against an aggressive Falcons defense.

For now, one thing is certain — the 49ers’ quarterback room has never been more intriguing. And for Mac Jones, Sunday’s loss wasn’t just the end of a perfect run — it was the beginning of his true test in red and gold.