The San Francisco 49ers may have defeated the Atlanta Falcons 20-10 on Sunday at Levi’s Stadium, but head coach Kyle Shanahan had more unfortunate injury updates for his team on Monday.

Shanahan addressed quarterback Brock Purdy’s toe injury and stated that he will continue to work like he did last week but he may not return to the field for the team’s Week 8 matchup with the Houston Texans.

If that’s the case, San Francisco will continue to ride with Mac Jones, who has brought them to a 4-1 record in his five starts.

Shanahan also shared the center Jake Brendel and linebacker Bryce Huff are both out a couple weeks due to hamstring injuries.

When Kyle Shanahan stepped up to the podium Monday afternoon, the usual calm confidence in his voice was gone. His eyes darted briefly toward the back of the room, almost as if searching for the right words before confirming what 49ers fans feared most — three of his key players had suffered more serious injuries than initially believed. The room went quiet. What began as a routine injury update quickly turned into a somber press conference.

The head coach revealed that linebacker Fred Warner, left tackle Trent Williams, and wide receiver Deebo Samuel were all facing extended absences. The news hit hard, not just because of who they were, but because of what they represented — the heartbeat, protection, and explosive soul of the San Francisco 49ers. “We’re going to have to regroup,” Shanahan admitted. “We’ve been through this before, but it never gets easier.”

The timeline painted a grim picture. Warner, the defensive captain, sustained a high ankle sprain during the second quarter of Sunday’s matchup. Williams aggravated a lingering knee issue that the team had hoped would improve with rest. And Samuel, always a fighter, was forced to exit after an awkward hit that left him clutching his shoulder. The trio’s collective absence could derail the momentum of one of the NFL’s most balanced squads.

For fans, it was déjà vu. Injuries have haunted the 49ers for years — from the 2020 collapse that followed a Super Bowl run to last season’s heartbreaking playoff stretch. Social media lit up immediately after the press conference. “This feels like 2020 all over again,” one fan posted. “You could see the pain in Kyle’s face. He knows what this means.”

The emotional toll was evident across the locker room. George Kittle, visibly shaken, told reporters, “You don’t replace guys like that. You just try to hold the line for them.” Even young quarterback Brock Purdy admitted the energy changed the moment Samuel left the field. “You feel it, man. It’s not just losing talent — it’s losing voices, energy, and belief.”

But amid the concern, Shanahan tried to steer the conversation toward resilience. “It’s a challenge,” he said, “but we’ve got depth. We’ve got a locker room that doesn’t back down.” His words carried conviction, but his tone betrayed worry. The next three weeks would define whether the 49ers could withstand another round of adversity — or crumble under the weight of expectations.

The upcoming schedule doesn’t help. A road trip to Cincinnati looms large, followed by a divisional showdown with Seattle. Every game matters. Every absence feels heavier. But perhaps what truly stands out in moments like this isn’t just the setbacks — it’s the sense of shared endurance between a team and its fans.

As the press conference ended, Shanahan paused before leaving. “We’ve got to stick together,” he said quietly. And in that brief silence before the next question, it was clear — everyone understood exactly what that meant.