NFL Rocked by Week 5 Injury News — Brock Purdy Out for 49ers, Jayden Daniels Practicing Hurt.tl

NFL teams are officially turning their attention to Week 5, and there’s good news in Washington.

Commanders head coach Dan Quinn said Wednesday morning that franchise quarterback Jayden Daniels has been cleared to practice in full. Marcus Mariota went 1-1 in Daniels’ stead, beating the Las Vegas Raiders his first start but losing to the Atlanta Falcons last week.

49ers QB Brock Purdy ruled out of Thursday night matchup with Rams due to  toe injury - Yahoo Sports

Daniels has been battling a knee sprain suffered in Week 2’s loss at the Green Bay Packers, and he wore a brace on Wednesday. “I plan on going out there Sunday,” Daniels said.

The San Francisco 49ers, meanwhile, are in a more dire spot. Quarterback Brock Purdy and wide receivers Jauan Jennings, Ricky Pearsall and Jordan Watkins were all ruled out for Thursday against the Los Angeles Rams, a critical NFC West road game.

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Lamar Jackson, meanwhile, didn’t practice Wednesday for the Baltimore Ravens with his hamstring injury, and his status for Sunday is in doubt. Jackson left last week’s loss to the Kansas City Chiefs with the injury, and if he can’t go, Cooper Rush will make the start. Head coach John Harbaugh characterized Jackson, like all Ravens injured players, as day to day.

San Francisco 49ers announce big decision about future of Brock Purdy

And the Cleveland Browns are making a big move at quarterback, with third-round rookie Dillon Gabriel taking over the starting job from veteran Joe Flacco. Gabriel’s first game will be in London Sunday against the Minnesota Vikings, which isn’t an ideal defense to face in any week, let alone your first NFL start. But Browns head coach Kevin Stefanski said the decision was his.

“[Gabriel] has handled everything well since he’s been on campus here. So just gonna have to support the young man,” Stefanski said Wednesday.

Stay on top of all the latest NFL news and developments right here.

San Francisco 49ers announce big decision about future of Brock Purdy

You can stream the Vikings-Browns London game and all prime time and out-of-market games on NFL+.

NFL news live blog

Follow along with Yahoo Sports for live updates, highlights and more following results from Week 4 of the 2025 NFL season:

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